More Elidel, Protopic and cancer
The American Academy of Allergy, Asthma and Immunology (AAAAI, usually called "quad-AI") has released it's expert panel report on the danger of topical immunomodulators and cancer here.
Not surprisingly, it says it is too early to draw conclusions and opposes the FDA decision to put a "Black box" warning on the producs, which are marketed as Elidel (pimecrolimus) and Protopic (tacrolimus). The report states out a pretty strong stance in favor of these medicines, stating they may even be used here, here and here.
posted by Dr. Andy @ 3:26 PM
4 Comments:
Your link to the report is a little messed up and doesn't work. The report can be found here instead.
Interesting report. Thanks for pointing it out. Sounds like the "black box" warning may be unwarranted. This debate is confusing and frustrating for patients.
If a patient were to follow the sensible original FDA guidelines for Elidel, I don't see how they could absorb enough of the drug to cause lymphoma or other cancers. It's the off-label use that might get someone into trouble. Off-label usage probably concerns the FDA because the pharmaceutical company heavily marketed the drug in ways that are counter to the FDA guidelines.
Paula
Hello,
My son developed severe eczema shortly after he was born. By three months old doctors gave me elidel and protopic and insisted it was safe and told me to put it on him every day three times per day. He had open, oozing eczema, so you know this stuff entered his bloodstream. By one he had started having health issues, including mysterious problems with his immune system and what appeared to be Kawasaki disease and now he has asthma and food allergies. He has had blood test that were not normal, the last one was better, but I'm very afraid. What can I do? How long does this crap stay in a person's body? Should he be tested regularly? He is three now, and has been off of elidel and protopic for about nine to so months.
Tamie
tamiep@gmail.com
wonderful news, is so soon the season in all those illness hit with more strong, specially the people who suffer of Asthma.
Eczema and skin disorders are related to gut imbalance. In fact, all diseases begin in the gut (Hippocrates said that thousands of years ago), as does mental health! Do not use these cancer-causing cremes! You need to change your diet. GAPS diet (Gut and Psychology Syndrome by Dr. Natasha Campbell-McBride) is known to heal and repair the digestive system so that the body can use food properly and be healthy inside and out! It has healed skin problems in my family, as well as helped me with depression. Autistic kids have benefited greatly from it. Good nutrition is the key to everything going well in your body and mind. You must change what you are eating/feeding your child to get rid of eczema and skin disorders.
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